Customization: | Available |
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CAS No.: | 000-0000-0 |
Formula: | 000-0000-0 |
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Molecular formula of Azelaic acid: C9H16O4
CAS number 123-99-9
Alias: azelaicacid,technicalgrade;Azelainic acid;Emerox 1110;Emerox 1144;emerox1110;emerox1144;Emery's L-110;ninandioic acid
Azelaic acid is a topical antiacne agent which exerts its therapeutic action through a myriad of antimicrobial, antiproliferative and cytostatic effects.
Azelaic acid Chemical Properties |
Melting point | 98 °C |
Boiling point | 286 °C100 mm Hg(lit.) |
density | 1,029 g/cm3 |
vapor density | 6.5 (vs air) |
vapor pressure | <1 mm Hg ( 20 °C) |
refractive index | 1.4303 |
Fp | 215 °C |
storage temp. | Store below +30°C. |
solubility | 2.4g/l |
pka | 4.53, 5.33(at 25ºC) |
form | Slightly Crystalline Powder or Flakes |
color | White to slightly yellow |
Application | Polymers and related materials Esters of this dicarboxylic acid find applications in lubrication and plasticizers. With hexamethylenediamine azelaic acid forms Nylon - 6,9, which finds specialized uses as a plastic. Medical Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne . It belongs to a class of medication called dicarboxylic acids. It works by killing acne bacteria that infect skin pores. It also decreases the production of keratin, which is a natural substance that promotes the growth of acne bacteria Azelaic acid is also used as a topical gel treatment for rosacea, due to its ability to reduce inflammation . It clears the bumps and swelling caused by Rosacea. Azelaic acid has been used for treatment of skin pigmentation including melasma and post inflammatory hyper pigmentation , particularly in those with darker skin types. It has been recommended as an alternative to (HQ). As a tyrosinase inhibitor, azelaic acid reduces synthesis of melanin. Brand names AzClear Action ( 20 % lotion, Ego Pharmaceuticals), Azelex (20% cream, Allergan), White Action cream (20 % cream ,2 % glycolic acid), SynCare), Finacea (15 % gel, Intendis/Berlex Laboratories, subsidiaries of Bayer AG), Finevin (20 % cream, Intendis / Berlex Laboratories), Skinoren (20 % cream or 15% gel, Intendis), Melazepam, Strata Dermatologics, 2oz, Mixed Dicarboxylic Acids 20 % Azelaic Acid Cream.,and Azaclear (azelaic acid and niacinamide, Epikinetics LLC). . |
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