| CAS No.: | 19883-41-1 |
|---|---|
| Formula: | C9h12clno2 |
| EINECS: | 243-399-9 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Medical Trade |
| Samples: |
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| Customization: |
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D-phenylglycine methyl ester is an important intermediate in the synthesis of ce faclor and am picillin. Ce faclor and am picillin are semi-synthetic second-generation cephalosporins with antibacterial spectrum and antibacterial activity similar to cef azolin. They are mainly used in the treatment of otitis media, lower respiratory tract infection, urinary tract infection, skin and skin tissue infection, and can inhibit all haemophilus influenzae bacteria. Including strains resistant to am picillin. Although the process reported in the synthesis patent is simple, the final product is D-phenylglycine methyl ester hydrochloride, and the synthesis of cephalox and am picillin requires desalination, which brings cumbersome processes to the subsequent synthesis, so the free D-phenylglycine methyl ester can be obtained at low cost and has commercial value.
| Item | Specification |
| Appearance | White crystalline powder |
| Contect | 99.9% |
| Density |
1.126g/cm3 |
| Boiling point |
238.9ºC at 760mmHg |
| Melting point |
189-191 °C(lit.) |
| Flash(ing) point |
104.7ºC |
| Storage condition |
2-8ºC |
|
Steam pressure |
0.0412mmHg at 25°C |
Scope of application:
D-phenylglycine methyl ester is an important intermediate for the synthesis of ce faclor and am picillin. Ce faclor and am picillin are semi-synthetic second-generation cephalosporins with similar antibacterial spectrum and antibacterial activity to ce fazolin. They are mainly used in the treatment of otitis media, lower respiratory tract infection, urinary tract infection, skin and skin tissue infection, and can inhibit all haemophilus influenzae. Including strains resistant to am picillin.
Dalian Sinobio Chemistry Co.,Ltd was established in 2011 and located in beautiful costal city Dailan Liaoning Province. we can enjoy convenient transportation by all logistic ways . The key funders have more than 16 years experience on the chemical indudstry. The mainstream products include Biocides, pharmaceutical and functional chemicals. Such as carbomer940, Ethyl alcohol, PHMB20% ,SLES70%,BKC 50%/80%,ZPT, IPBC, Glutaraldehyde 50%, Sitagliptin and so on. During the pass 10 years, we gained a bunch of loyalty customers due to high quality products and the best services, and we have cooperated with multi-national company such as DOW,LANXESS, THOR etc. for more than 10years
Dalian Sinobio Chemistry Co.,Ltd are making great efforts to develop new products to meet customers' requirements. Warmly welcome customers from at home and abroad to cooperate with us for common success.
Q1: Can I get samples?
A: Yes, we can supply free sample, you pay for the freight charge only.
Q2: How to pay?
A: PI will be sent firstly after our aligned products specification. Payment by Paypal , T/T, Western Union,LC, Alipay are ok
Q3: How is your MOQ?
A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q4: How can you guarantee the quality of your products?
1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.
2. Free sample or pre- shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers
3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.
4. On-Spot QC in our APPROVED associated production bases with necessary certification like GMP, ISO etc.
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